Pharmaceutics Research Group

1. Formulation And In-Vitro In-Vivo Evaluation Of Gastro Retentive Multiparticulate Drug Delivery System Of Cimetidine.

Formulation of microparticles of cimetidine and their invitro charterisation by dirrefent techniques e.g SEM, FTIR and XRD and then invivo evaluation of the selective formulation using normal human volunteers for the pharmacokinetic parameters evaluation.


Project Funding
 Funding Body Funds
1 CIIT no logo 200000 Rs


Project Members
  • Dr. Ghulam  Murtaza
  • Dr. Shujaat Ali  Khan
  • 2. Development Of Self-Microemulsifying Drug Delivery Systems For Enhanced Bioavailability Of Poorly Water Soluble Drugs

    In this study the self-microemulsifying drug delivery systems (SMEDDS)of poorly water-soluble drugs (anticancer, antifungal, antihypertensive, NSAIDs, antipsychotics etc) will be developed to increase the drug solubility and absorption in GIT. SMEDDS have been known for their numerous advantages like spontaneous formation, ease of manufacture, stability, and improved solubilization, faster release rates and better availability in the blood, which leads to lesser drug dose, lower cost, and reduced stomach irritation and toxicity; thus ultimately improving drug acceptance by the consumers. SMEDDS will be prepared and evaluated in comparison with other commercially available medicines for blood concentration in mice. Thus, safe and highly cost effective formulations of water insoluble drugs will be developed which will be new hope for patients and an attraction for pharmaceutical industry.

    Project Members
  • Mubashar Ali  Abid
  • 3. Development Of Self-Emulsifying Drug Delivery System For Enhanced Bioavailability Of Poorly Water Soluble Drugs”

    In this study the self-microemulsifying drug delivery systems (SMEDDS)of poorly water-soluble drugs (anticancer, antifungal, antihypertensive, NSAIDs, antipsychotics etc) will be developed to increase the drug solubility and absorption in GIT. SMEDDS have been known for their numerous advantages like spontaneous formation, ease of manufacture, stability, and improved solubilization, faster release rates and better availability in the blood, which leads to lesser drug dose, lower cost, and reduced stomach irritation and toxicity; thus ultimately improving drug acceptance by the consumers. SMEDDS will be prepared and evaluated in comparison with other commercially available medicines for blood concentration in mice. Thus, safe and highly cost effective formulations of water insoluble drugs will be developed which will be new hope for patients and an attraction for pharmaceutical industry

    Project Members
  • Dr.  Nisar-ur-Rahman
  • 4. Development Of Gastroprotective Drug Delivery System Using Synthesized Copolymeric Nanocomplexes: Characterization And Biological Evaluation

    Biomaterials and Its Applications in Medicine/Drug Delivery. Nanocomplexes formation and their In Vitro Characterization.

    In Vivo Studies in Animal Models.


    Project Funding
     Funding Body Funds
    1 Higher Education Commission, Pakistan no logo 419750 Rs


    Project Members
  • Dr. Muhammad Sohail
  • 5. PEGYLATED PROTAMINE – RECOMBINANT HUMAN INTERLEUKIN 24 AND DOXORUBICIN NANOPARTICLES FOR SINGLE COMBINATION THERAPY OF CANCER

    PEGYLATED PROTAMINE – RECOMBINANT HUMAN INTERLEUKIN 24 AND DOXORUBICIN NANOPARTICLES FOR SINGLE COMBINATION THERAPY OF CANCER


    Project Funding
     Funding Body Funds
    1 HEC no logo 2.071838 Rs


    Project Members
  • Dr. Muhammad Imran  Amirzada
  • 6. An Innovative Approach To Green Cosmetic Formulations From Food Waste Of Pakistan

    Pakistan is an agricultural country, where a large number of fruits and vegetables are harvested. A big portion of food waste is generated in agricultural, industrial and household activities. This food waste includes; peels of mango, citrus fruits, apple, banana, cucumber bran of rice, bran and germs of wheat, skin and pomace of tomato and seeds etc. This food waste contained a large number of valuable bioactive compounds. If we use this food waste in proper way for the manufacturers without exhausting, then we can get broader impacts of ecological, social and economic as Pakistan is a developing country. We are pursuing for an innovative approach to use this food waste of Pakistan to green cosmetics to achieve sustainable development goals. For this purpose, main food waste will be targeted and extracted. Green cosmetic formulations will be promoted from these food waste extracts using nanotechnology. Stability of developing formulations will be checked. Then, these formulations will be tested on animals. After checking the safety and efficacy of formulations, they will be tested on human subjects. Green cosmetic formulations by using food waste will make attractable to our community and cosmetic manufacturers to compete market demands.
     

    Project Funding
     Funding Body Funds
    1 HEC no logo 6.33 Million Rupee


    Project Members
  • Dr Atif Ali
  • Dr. Abdul  Mannan