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Faculty Profile

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Dr Nighat Fatima

Tenured Associate Professor
Area of Interest: Pharmaceutical Biotechnology (Natural Product Chemistry, Biological Activities)
Email: nighatfatima@cuiatd.edu.pk
Phone: +92-992-383591-5
 
Academics/ Degrees
  • Fulbright Postdoctoral Fellowship, College of Pharmacy, The Ohio State University, USA, 2019
  • PhD, Quaid-i-Azam University, Islamabad, Pakistan, 2013
  • M.Phil, Quaid-i-Azam University, Islamabad, Pakistan, 2007
  • B-Pharmacy, Punjab University Lahore, 2001
 
Journal Publications
1. A. Mannan,Sohail Anjum Shahzad,Dr. Nighat Fatima,T.Ismail Exploring the antimicrobial and cytotoxic potential of novel chloroquine analogues, Future Medicinal Chemistry , 2024
2. Shahnaz Rahim,Dr. Nighat Fatima,Niaz Muhammad,Aneela Javed Synthesis, characterization, enzyme inhibition, antioxidant, anticancer and antimicrobial potential of organotin (IV) derivatives of 4-fluorophenoxyacetic acid, Arabian Journal of Chemistry, 2024
3. Dr. Nighat Fatima,T.Khan,I.Shahzadi Assessment of Cytotoxic potential of newly isolated Betulinic triterpenes from the Bark of Bauhinia variegata Linn. (Caesalpiniaceae), South African Journal of Botany, 2023
4. A. Mannan,Dr. Nighat Fatima Cytotoxic, in vitro Enzyme Inhibitory Potential and Phytochemical Profiling of Odontonema strictum, Pharmacognosy Magazine , 2023
5. I.Shahzadi,M.Shah,A. Baig,M.Siddique,T.Ismail,Dr. Nighat Fatima,Syed Munawar Aziz Shah Antioxidant, Cytotoxic, and Antimicrobial Potential of Silver Nanoparticles Synthesized using Tradescantia pallida Extract, Frontiers in Bioengineering and Biotechnology, 2022
6. Jean P. Dzoyem,G. Murtaza,I.Shahzadi,A. Mannan,Dr. M. Arfat Yameen,T.Ismail,Dr. Nighat Fatima,Dr. Jamshed Iqbal,,Roland T. Tchuenguem Anticandidal activity of green synthesized silver nanoparticles and extract loaded, chitosan nanoparticles of Euphorbia prostata, Artificial Cells, Nanomedicine, and Biotechnology, 2022
7. Dr. Nighat Fatima,Dr. Jamshed Iqbal Anticandidal activity of green synthesized silver nanoparticles and extract loaded chitosan nanoparticles of Euphorbia prostata, Artificial Cells, Nanomedicine and Biotechnology, 2022
8. Nikhat Ilahi,Safia Ahmed,Dr. Nighat Fatima,Abdul Haleem,Sajjad Iqbal,Waseem Sajjad ,Abubakar Sideeqe Biosynthesis of silver nanoparticles using endophytic Fusarium oxysporum strain NFW16 and their in vitro antibacterial potential, Microscopy research and technique, 2022
9. Dr. Nighat Fatima,I.Shahzadi,A. Mannan,Dr. M. Arfat Yameen,T.Ismail,I.Amirzada,Syed Aun Muhammad,Hina Tariq,G. Murtaza Photodynamic cytotoxic and antibacterial evaluation of Tecoma stans and Narcissus tazetta mediated silver nanoparticles, Arabian Journal of Chemistry, 2022
10. M.Siddique,Dr. AM Abbasi,M.Bilal,R.Khan,I.Shahzadi,Dr. Nighat Fatima Green Synthesis of Silver Nanoparticles and Nano-Adsorbents Having Potential in Ultrasound-Assisted Adsorptive Removal of Methylene Blue Dye from Wastewater and Antimicrobial Activity, Materials, 2022
11. Dr. Nighat Fatima,I.Shahzadi,A. Mannan,T.Ismail,T.Khan,K.Yousaf,Ihsan-ul-Haq,Saniya Zahra,MH Asim Phytochemical and biological attributes of Bauhinia variegata L. (Caesalpiniaceae). , Brazilian Journal of Biology, 2022
12. Ehsan Ullah Mughal,Masoud Mirzaei,Amina Sadiq,Sana Fatima,Ayesha Naseem,Nafeesa Naeem,Dr. Nighat Fatima,Samia Kausar,Ataf Ali Altaf,Muhammad Naveed Zafar,Bilal Ahmad Khan Terpyridine-metal complexes: effects of different substituents on their physico-chemical properties and density functional theory studies, 25 November , 2020
13. Zainab Jamil,Syeda Tahira Qousain Naqvi,Sumaira Rasul,Syed Bilal Hussain,Dr. Nighat Fatima,Muhammad Imran Qadir,Syed Aun Muhammad Antibacterial activity and characterization of zinc oxide nanoparticles synthesized by microalgae, 1 November , 2020
14. Jamshaid Ashraf,Ehsan Ullah Mughal ,Amina Sadiq, Maryam Bibi, Nafeesa Naeem, Anam Massadaq, Anser Ali,Dr. Nighat Fatima,Asif Javid,Muhammad Naveed Zafar,Bilal Ahmad Khan,Muhammad Faizan Nazar,A.Mumtaz,Muhammad Nawaz Tahir ,Masoud Mirzaei Exploring 3-Hydroxyflavone Scaffolds as Mushroom Tyrosinase Inhibitors: Synthesis, X-Ray Crystallography, Antimicrobial, Fluorescence Behaviour, Structure-Activity Relationship and Molecular Modelling Studie, JOURNAL OF BIOMOLECULAR STRUCTURE AND DYNAMICS, 2020
15. Ehsan Ullah Mughal,Hafiz Umar Farooq, Amina Sadiq, Hummera Rafique,Sajjad Hussain Sumrra,Muhammad Naveed Zafar,Dr. Nighat Fatima,Syed Aun Muhammad,A. Mannan, Chaudhary Omer Javed,, Muhammad Tayyab An Efficient Protocol for the Synthesis, Biological Screening and Molecular Docking Studies of 3,4-Dihydropyrimidine-2-one/thione Derivatives, 20 April , 2020
16. Muhammad Latif,Muhammad Ihtisham Umar,Asim Rahim,Shujaat A.K, SA Khan,Dr. Nighat Fatima, Izhar Hussain,A. Mannan,Mohamed Khadeer Ahamed Basheer Isolation and biological evaluation of some secondary metabolites from seeds of Silybum marianum, 1 March, 2020
17. Dr. Nighat Fatima,Dr. M. Arfat Yameen,I.Shahzadi,Dr. Jamshed Iqbal,Muhammad Raf Datura suaveolens and Verbena tenuisecta mediated silver nanoparticles, their photodynamic cytotoxic and antimicrobial evaluation, 11, February , 2020
18. Dr. Jamshed Iqbal,Dr. Nighat Fatima, Ahsan Ashraf Datura suaveolens and Verbena tenuisecta mediated silver nanoparticles, their photodynamic cytotoxic and antimicrobial evaluation. World Journal of Microbiology and Biotechnology, World Journal of Microbiology and Biotechnology , 2020
19. Anam Shahzadi,Fakhera Ikram,Riaz Ul Haq Subhani,Arsalan Ahmed,Anila Asif,Dr. Nighat Fatima,Aqif Anwar Chaudhry,Yong Hu Acid susceptible polymeric stealthy nanoparticles for improved anticancer drug delivery, 11 December , 2019
20. A Ali,Dr. Nighat Fatima,Asad. M.H.H.B Anti-pollution cosmetic-based one-step formation of w/o/w multiple emulsion containing D-biotin for skin protection: fabrication and in vitro and in vivo evaluation, Drug Delivery and Translational Research, 2019
21. M.Shah,R.Ahmad,Dr. Nighat Fatima Bioactivity-guided isolation of rosmarinic acid as the principle bioactive compound from the butanol extract of Isodon rugosus against the pea aphid, Acyrthosiphon pisum., PloS ONE, 2019
22. Hina Rahim,Muhammad Saleem,Abdur Rauf,Abdul Wadood,M. Imran malik,Ayaz Ahmad,Hummera Rafique,Muhammad Naveed Zafar,Muhammad Riaz,Aneela Maalik,Lubna Rasheed,A.Mumtaz,Dr. Nighat Fatima Synthesis, antimicrobial, antioxidant, cytotoxic, antiurease and molecular docking studies of N-(3-trifluoromethyl)benzoyl-N’-aryl thiourea derivatives, Bioorganic Chemistry, 2019
23. Syed Aun Muhammad,Dr. Nighat Fatima,Rehan Zafar Paracha,Amjad Ali ,Jake Y. Chen A systematic simulation-based meta-analytical framework for prediction of physiological biomarkers in alopecia, 4, April , 2019
24. Rimsha Khan,Syeda Tahira Qousain Naqvi,Dr. Nighat Fatima,Syed Aun Muhammad Study of antidiabetic activities of endophytic fungi isolated from plants. , 19 April , 2019
25. A. Mannan,Shujaat A.K, SA Khan,Dr. Nighat Fatima,Dr. AM Abbasi Evaluation of antioxidant, antimicrobial and cytotoxic potential in Artemisia vulgaris L., Romanian Journal of Laboratory Medicine, October 01, 2018, 2018
26. Dr. Nighat Fatima,Shams Ur Rehman,Muhammad Dawood,Muneer Ahmed Qazi,Muhammad Soaib Said Targeted Based Drug Designing of Pimarane Diterpenes as Potential Inhibitors of New Delhi-Beta-Lactamase, Pakistan Journal of Zoology , 2018
27. Dr. M. Arfat Yameen,Dr. Nighat Fatima,Zainab Gul Knawal Implications of self-medication among medical students-A dilemma, Journal of The Pakistan Medical Association, 2018
28. A. Mannan,A.Nazir,Dr. Nighat Fatima,Shujaat A.K, SA Khan,Yasser MSA Alkahraman Antioxidants, antimicrobial and cytotoxic potential of Swertia chirata, Biomedical Research, September 01, 2018, 2018
29. A.Maalik,Sadia Hameed,Huma Aslam Bhatti,Abdur Rauf,S. M. Bukhari,Dr. Nighat Fatima,Hummera Rafique,Ihsan Ullah Mughal,A.Mumtaz Synthesis and Biological screening of N,N’-bisdisubstitutedadipic acid thioureas, Current Pharmaceutical Analysis , 2018
30. T.Ismail,Dr. Nighat Fatima,A. Mannan,I.Amirzada Prioritizing and modelling of putative drug target proteins of Candida albicans by systems biology approach, Acta Biochimica Polonica, 2018
31. MOHSIN ABBAS KHAN,Dr. Nighat Fatima,Dr. M. Arfat Yameen Synthesis, Characterization and In-Vitro Biological Screening of Triphenyltin Derivative of Isoniazid Hydrazones., Acta Polionica Pharmaceutica-Drug Research, 2018
32. Ehsan Ullah Mughal,Amina Sadiq,Muhammad Hamayun,Muhammad Naveed Zafar,Syed Aun Muhammad,A.Mumtaz,Dr. M. Arfat Yameen,Ishtiaq Ahmed, Tehseen Fatima,Dr. Nighat Fatima "Design, Synthesis and Biological Evaluation of Novel Dihydropyrimidine-2-Thione Derivatives as Potent Antimicrobial Agents: Experimental and Molecular Docking Approach" , Letters in Drug Design & Discovery, 2018
33. Dr. Nighat Fatima,Abida K Khan,A.Maalik,A. Mannan,A.Mumtaz Fungal Metabolites and Antimalarial Drug Discovery; A Review, Acta Poloniae Pharmaceutica-Drug Research, October 23, 2017, 2017
34. Syed Aun Muhammad,Muneer Ahmed Qazi,Zia ulAllah Shah,Hummera Rafique,Muhammad Dawood,A.Mumtaz,Dr. Nighat Fatima,Abida K Khan,A.Maalik,A. Mannan Fungal metabolites and antimalarial drug discovery; A review , Acta Poloniae Phaermaceutica-Drug Research, 2017
35. Dr. Nighat Fatima, Ui J. Youn, Safia Ahmed, Ihsan ul-Haq,Ulyana Munoz-Acuna,Charles J. Simmons, Muneer A. Qazi, Muniba Jadoon, Ghee T. Tan, Tawanun Sripisut, Esperanza J.C. de Blanco, Leng C. Chang Bioactive Constituents from an Endophytic Fungus, Penicillium polonicum NFW9, Associated with Taxus fauna., Journal, 2017
36. Mohsin Abbas Khan,Samar Akhtar,Khadija Shahid,Syed Aun Muhammad,Amara Mumtaz,Muhammad Arfat Yameen,Dr. Nighat Fatima Synthesis, Characterization And In-vitro Biological Screening Of Triphenyltin Derivative Of Isoniazid Hydrazones, 3 May , 2017
37. Naqvi, Syeda Tahira Qousain,Shah, Ziaullah;,Dr. Nighat Fatima,Qadir, Muhammad Imran,Ali, Amjad,Muhammad, Syed Aun Characterization and Biological Studies of Copper Nanoparticles Synthesized by Aspergillus niger, 1 April, 2017
38. T.Ismail,Syed Aun Muhammad,Fareeha Anwar,.Nisar-ur-Rahman,A. Mannan,Dr. Nighat Fatima BIOLOGICAL SCREENING OF ENDOPHYTIC FUNGI ISOLATED FROM NERIUM OLEANDER , INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES, November 2016, 2016
39. Humera Rafique,Muhammad Dawood,A.Mumtaz,Dr. Jamshed Iqbal,Dr. Nighat Fatima,Aamer Saeed Imidazole and their derivatives potential candidates for the drug development: A review, Bangladesh Journal of Pharmacology, 2016
40. A. Mannan,Syed Aun Muhammad,Fareeha Anwar,I.Amirzada,.Nisar-ur-Rahman,Dr. Nighat Fatima,T.Ismail AN EMERGING PARADIGM EXOSOMES: COMPOSITION, BIOLOGICAL FUNCTIONS, AND DIAGNOSTIC AND THERAPEUTIC POTENTIALS, INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES, October 2016, 2016
41. Sidra Rehman,Syed Aun Muhammad,Sheikh Riazuddin,Dr. Nighat Fatima,Bushra Ijaz Therapeutic potential of Taraxacum officinale against HCV NS5B polymerase: in-vitro and in silico study, Biomedicine and Pharmacotherapy , 2016
42. Zainab Gul Kanwal,Abdul Hafeez,Ihsan Ul Haq,Tofeeq-Ur-Rehman,Syed Aun Muhammad,I.Shahzadi,Dr. Nighat Fatima,.Nisar-ur-Rahman Antioxidant, Antimicrobial and Antileishmanial Study of Different Parts of Peganum harmala, July 18, 2016
43. Ibrar Khan,Sadia Qayyum,Shehzad Ahmed,Zeeshan Niaz,Zhen-Ming Chi,Dr. Nighat Fatima Molecular cloning and sequence analysis of a PVGOX gene encoding glucose oxidase in Penicillium viticola F1 strain and it's expression quantitation., July 15, 2016
44. Hina Tariq,Muhammad Soaib Said,Muhammad Dawood,Dr. Nighat Fatima,A.Mumtaz,I.Shahzadi,Syed Aun Muhammad Fungal Metabolites and Leishmaniasis: A Review, 20 June, 2016
45. Dr. Nighat Fatima,Syed Aun Muhammad,Ibrar Khan,I.Shahzadi,A.Mumtaz,Muneer Ahmed Qazi,Muhammad Ali Hashmi,Abida K Khan,T.Ismail Chaetomium endophytes: a repository of pharmacologically active metabolites, Acta Physiologiae Plantarum, 2016
46. Dr. Nighat Fatima,A.Mumtaz,Rahat Shamim,Muhammad Imran Qadir,Syed Aun Muhammad In Silico Analyses of Epicoccamides on Selected Leishmania Trypanothione Reductase Enzyme-based Target, 23April, 2016
47. Amara Mumtaz,Syed Aun Muhammad,Sidra Rehman,Dr. Nighat Fatima,I.Shahzadi,Q.Mahmood,Muhammad Dawood Molecular Docking Studies of Sesquiterpenoids against Helicobacter pylori Peptide Deformylase, British Journal of Pharmaceutical Research , 2016
48. A.Mumtaz,TARIQ ISMAIL,SYED AUN MUHAMMAD,MUNIBA JADOON,SAFIA AHMED,S.Azhar,Dr. Nighat Fatima EPICOCCUM SP., AN EMERGING SOURCE OF UNIQUE BIOACTIVE METABOLITES, Acta Poloniae Pharmaceutica ñ Drug Research, 2016
49. A.Mumtaz,A.Maalik,Khan, W,S.Azhar,Dr. Nighat Fatima,A. Zaidi,M. Atif Synthesis, characterization and biological screening of 1-aroyl-3,5-diarylpyrazolines, Acta Pol. Pharm. Drug Res., 2015
50. Dr. Nighat Fatima MicroRNA Expression Profiling of Human Respiratory Epithelium Affected by Invasive Candida infection, PLOS1, 15 Augest, 2015
51. Dr. Nighat Fatima In silico analysis and molecular docking studies of potential angiotensin-converting enzyme inhibitor using quercetin glycosides, Pharmacognosy Magazine, 2015
52. Abida K Khan,R.Rashid,Dr. Nighat Fatima,Sadaf Mahmood,S.Mir,Sara Khan,Nyla Jabeen Pharmacological activities of Protocatechuic Acid, Acta Poloniea Pharmaceutica Drug Research, 2015
53. Dr. Nighat Fatima In silico analysis and molecular docking studies of potential Angiotensin Converting Enzyme (ACE) inhibitor using quercetin glycosides, Pharmacognosy Magazine, 2015
54. Dr. Nighat Fatima,Abida K Khan,A.Mumtaz,Syed Aun Muhammad Computational drug designing of fungal pigments as potential aromatase inhibitors, Bangladesh Journal of Pharmacology , 2014
55. A.Mumtaz,Aamer Saeed,S.Azhar,Dr. Nighat Fatima,G. Murtaza Antimicrobial Activities of 2-(3,5-Dimethoxy-4-methylbenzyl)-5-aryl-1,3,4-oxadiazoles, Latin American Journal of Pharmacy, 2014
56. Dr. Nighat Fatima Isolation and characterization of a biosurfactant-producing Fusarium sp. BS-8 from oil contaminated soil, Bioseparations and Downstream Processing, 21 May, 2014
 
Conference Publications
 
Profile/Bio
PROFESSIONAL AND RESEARCH EXPERIENCE
  • Sept. 2013 to Nov. 2013: Visiting Assistant Professor, Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan
  • March 2011 to March 2012: IRSIP Research Scholar at College of Pharmacy, University of Hawaii at Hilo, 96720,Hawaii USA
  • Feb. 2002 to June 2003: Hospital pharmacist at Emirates Medical College Wah Cantt., Pakistan
 
 
Research Interests
  • Production, isolation and structural characterization of bioactive metabolites from microorganisms/plants. Biological assays: Antibacterial, Antifungal, Antioxidant, Antitumor, Cytotoxic Protein kinase inhibition and Cancer chemopreventive assays
  • Structural characterization of unique compounds mechanism study at molecular level for drug development